Table 1.
Resource usagea | Mean values reported by the expert panel | ||||
---|---|---|---|---|---|
DAPTO | LINE | TEICO | TIGE | VANCO | |
No. of days of treatmentb | 9.8 | 9.2 | 11.5 | 11.7 | 11.8 |
No. of days in hospitalc | 10.3 | 9.2 | 14.0 | 13.0 | 12.5 |
No of days IV | 9.8 | 6.7 | 12 | 11.7 | 11.8 |
Average daily dose (mg)d | 458 | 1,200 | 500 | 133 | 2,000 |
IV doses per day | 1.0 | 2.0 | 1.0 | 2.0 | 2.0 |
No. of days oral | 0.0 | 2.5 | 0.0 | 0.0 | 0.0 |
Oral doses per day | 0.0 | 2.0 | 0.0 | 0.0 | 0.0 |
Additional no. of days in hospital due to AE | 5 | 5 | 5 | 5 | 5 |
Additional no. of days in hospital due to treatment failure | 7 | 7 | 7 | 7 | 7 |
AE adverse events, DAPTO daptomycin, IV intravenous, LINE linezolid, TEICO teicoplanin, TIGE tigecycline, VANCO vancomycin
aValues are calculated as means of expert panel feedback
bExcluding the treatment time prior to cultivation results
cTime from hospital admission to discharge
dEstimated for a ‘typical’ 75 kg patient