Fig. 7.

Pharmacological inhibition of PKA with H-89 or KT-5720 significantly increased spontaneous phasic contractions of isolated UBSM strips. A and B: representative recordings of UBSM strips illustrating that pharmacological PKA inhibition increases UBSM spontaneous phasic contractions. C and D: summary data illustrating the effects of PKA inhibition with H-89 (10 μM; n = 14, N = 10) or KT-5720 (3 μM; n = 8, N = 5) on the amplitude (Amp), muscle force integral (Force), duration (Dur), frequency (Freq), and tone of UBSM spontaneous phasic contractions. *P < 0.05.