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. 2014 Oct 15;307(12):R1448–R1457. doi: 10.1152/ajpregu.00312.2014

Fig. 2.

Fig. 2.

Experiment 2A. Intragastric (IG) sugar conditioning in ad libitum-fed FVB mice trained 24 h/day. Intake of the conditioned stimulus (CS)+ solution was paired with IG infusions of either 16% fructose (A) or 16% glucose (B). Intake of the CS− solution was paired with IG infusions of water. The left side of each panel shows total daily fluid intake (oral CS intake plus IG infusate) during each of the six one-bottle training days. The CS− solution was offered on days 1, 3, and 5, and the CS+ solution was offered on days 2, 4, and 6. The right side of each panel shows mean total daily intake during the reinforced (Rein) two-bottle preference test, in which the CS+ was paired with IG sugar infusion, and mean daily intake during the nonreinforced (NR) two-bottle test, in which the CS+ was paired with IG water infusion. Values are expressed as means ± SE total daily intakes. Numbers atop bars represent mean percent preference for the CS+ solutions. Significant differences (*P < 0.05) between CS+ and CS− intakes during one-bottle training and two-bottle tests are shown.