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. 2014 Oct 17;307(12):L987–L997. doi: 10.1152/ajplung.00063.2014

Fig. 7.

Fig. 7.

Dihydrobiopterin expression does not contribute to LPS-induced permeability in HLMVEC in vitro. A: biopterin expression in HLMVEC following LPS (1 μg/ml for 4 h) exposure in the presence or absence of BH4 (50 μM). Bars represent means ± SE from n = 4 individual experiments, P = NS. Biopterin expression is minimal in HLMVEC at baseline and following LPS exposure. B: HLMVEC permeability (basal dextran fluorescence) following LPS (1 μg/ml for 4 h) exposure in the presence or absence of BH2 (50 μM). BH2 exposure has no effect on HLMVEC monolayer permeability at baseline or following LPS exposure. Bars represent means ± SE from n = 8 individual experiments, P = NS.