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F=20 ml/100 g/min; Vb=2 ml/100 g/min. Estimated Ki (y-axis) based on 1,000 simulations plotted against true Ki (x-axis). Dotted line represents the identity line. Vertical full lines represent the precision of the measurement (s.d. 2). eTofts, extended Tofts model; F, cerebral blood flow; Ki, permeability; Tik-2C, Tikhonov two-compartment model; Vb, cerebral blood volume.
