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Accumulation of radioactivity in the brain after intravenous injection of [3H]Hydromethidine to mice treated with sodium nitroprusside (SNP) (20 nmol). SNP was microinjected to the right striatum. (A) Typical autoradiograms in brain obtained at 1, 5, 20, and 60 minutes after [3H]Hydromethidine injection. (B) Radioactivity profiles in the SNP-injected striatum (●) and saline-injected striatum (○), calculated from the autoradiograms. Data are expressed as (PSL-BG)/mm2 (mean±s.d., n=4).
