Figure 2.

Comparison of the (scaled) f(t) versus R(t) plot for the three proposed models (a–c). Different curves correspond to different substrate rigidities. Dotted lines mark the steady-state. $R_{\text{ss}}^{\text{max}}$ and $f_{\text{ss}}^{\text{max}}$ are the steady-state radius and force for an infinitely rigid substrate, respectively. In all panels we took ξ_s/ξ_s^max = E_m/(E_m + E_c) = 0.5 (red), 0.67 (orange), 0.83 (green), and 0.99 (blue), where E_m and E_c are the respective Young’s moduli of the substrate and cell (5); see the Supporting Material for additional parameters used. To see this figure in color, go online.