Figure 6.

(a) Model predictions of static lumen radius for thickened airway wall (dashed curves) as a function of applied transmural pressure for increasing agonist $k_1$ (color coding as in Fig. 3). These are compared with the pressure-radius relationship for the normal airway (solid curves). Horizontal black arrows indicated shift from normal to remodeled airway. (b) Effective airway stiffness for the thickened airway (dashed curves) and normal airway (solid curves) determined by calculation of the reciprocal of the slope of the static pressure-radius curves in (a) plotted as a function of $P_{TM}$ for increasing agonist. Color coding is identical to (a). To see this figure in color, go online.