TABLE 5.
Regression results: factors associated with composite severe childhood morbidity at age 2 yearsa
Variable | OR | 95% CI | P value |
---|---|---|---|
PPROM prior to 25 wks’ gestation | 1.57 | 1.12–2.20 | .009 |
Severe composite neonatal morbidity | 2.13 | 1.56–2.90 | < .001 |
White | 0.82 | 0.63–1.06 | .123 |
Male infant | 1.56 | 1.22–2.00 | < .001 |
Delivery gestational age (per 1-wk interval) | 0.86 | 0.81–0.92 | < .001 |
Cesarean delivery | 1.31 | 1.02–1.68 | .031 |
Maternal drug use during pregnancy | 1.65 | 1.14–2.37 | .008 |
CI, confidence interval; OR, odds ratio; PPROM, preterm premature rupture of membranes.
Other factors included in the initial model but not remaining in the final model (P > .20) included chorioamnionitis and treatment group (magnesium sulfate vs placebo).
Manuck. Outcomes following early PPROM. Am J Obstet Gynecol 2014.