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| Group 1 | Group 2 | Effect size d | A priori power | Group 1 sample size | Group 2 sample size |
|---|---|---|---|---|---|
| pAKT, vehicle, PLX4720 | pAKT, HGF, PLX4720 | 2.943958 | 93.1%a | 4a | 4a |
6 per group will be used based on the pERK planned comparisons making the power 99.5%.
Note: HGF/PD184352 compared to vehicle/PD184352 is not included as the number of needed samples is too large.
