Reagent	Type	Manufacturer	Catalog #	Comments
96-well Tissue culture plates	Materials	Corning (Sigma-Aldrich)	CLS3596	Original unspecified
6-well tissue culture plates	Materials	Corning (Sigma-Aldrich)	CLS3516	Original unspecified
KHM-3S cells	Cells	JCRB Cell Bank	JCRB0138	Original source of the cells unspecified
A204 cells	Cells	ATCC	HTB-82	Original source of the cells unspecified
M14 cells	Cells	ATCC	HTB-129	Original source of the cells unspecified
HL60 cells	Cells	ATCC	CCL-240
MCF7 cells	Cells	ATCC	HTB-22
HEK293 cells	Cells	ATCC	CRL-1573
Lapatinib	Drug	LC Laboratories	L-4804	Original formulation unspecified
Crizotinib	Drug	Sigma-Aldrich	PZ0191	Originally from Selleck Chemicals
PD173074	Drug	Sigma-Aldrich	P2499	Originally from Tocris Bioscience
PLX4032	Drug	Active Biochem	A-1130
Sunitinib	Drug	Sigma-Aldrich	PZ0012	Originally from Selleck Chemicals, formulation unspecified
Erlotinib	Drug	LC Laboratories	E-4007
HGF	Ligand	Sigma-Aldrich	H5791	Originally obtained from Peprotech
FGF-basic	Ligand	Sigma-Aldrich	F0291	Originally obtained from Peprotech
NRG1-β1	Ligand	Novus Biologicals	P1426	Originally obtained from R&D Systems
RPMI 1640	Media	Sigma-Aldrich	R8758	Originally from Gibco, formulation unspecified
FBS	Reagent	Sigma-Aldrich	F4135	Originally from Gibco
Penicillin	Antibiotic	Sigma-Aldrich	P4458	Original unspecified
Streptomycin	Antifungal			Original unspecified
Halt protease and phosphatase cocktail inhibitor	Reagent	Thermo Scientific	78440
Image J	Software	National Institutes of Health (NIH)	N/A
p-PDGFRα	Antibody	Santa Cruz	SC-12911	190 kDa
PDGFRα	Antibody	Cell Signaling	5241	190 kDa
p-AKT S473	Antibody	Invitrogen	44-621 G	65 kDa
AKT	Antibody	Cell Signaling	9272	65 kDa
p-ERK T202/Y204	Antibody	Cell Signaling	9101	44,42 kDa
ERK	Antibody	Cell Signaling	9102	44,42 kDa
pFRS2α Y196	Antibody	Cell Signaling	3864	85 kDa
FRS2α	Antibody	Santa Cruz	SC-8318	85 kDa
β-tubulin	Antibody	Cell Signaling	2146	55 kDa
pHER3 Y1289	Antibody	Cell Signaling	4791	185 kDa
HER3	Antibody	Santa Cruz	SC-285	185 kDa
p-EGFR Y1068	Antibody	Abcam	ab5644	185 kDa
EGFR	Antibody	BD Biosciences	610017	185 kDa
p-MET Y1234/5	Antibody	Cell Signaling	3126	145 kDa
MET	Antibody	Santa Cruz	SC-10	145 kDa
Anti-Mouse IgG-HRP	Antibody	Cell Signaling Technology	7076P2	Original unspecified
Anti-Rabbit IgG-HRP	Antibody	Cell Signaling Technology	7074P2	Original unspecified
Anti-Goat IgG-HRP	Antibody	Santa Cruz Biotechnology	sc-2020	Original unspecified
Trypsin-EDTA solution (1X)	Reagent	Sigma-Aldrich	T3924	Original unspecified
Dulbecco’s Phosphate Buffered Saline	Reagent	Sigma-Aldrich	D1408	Original unspecified
Mini Protean TGX 4–15% Tris-Glycine gels; 15-well; 15 μl	Reagent	Bio-Rad	456-1086	Original unspecified
2X Laemmli sample buffer	Reagent	Sigma-Aldrich	S3401	Original unspecified
ECL DualVue Western Markers (15 to 150 kDa)	Reagent	Sigma-Aldrich	GERPN810	Original unspecified
Nitrocellulose membrane; 0.45 μm, 20 × 20 cm	Reagent	Bio-Rad	162-0113	Original unspecified
Ponceau S	Reagent	Sigma-Aldrich	P7170	Original unspecified
Tris Buffered Saline (TBS); 10X solution	Reagent	Sigma-Aldrich	T5912	Original unspecified
Tween 20	Reagent	Sigma-Aldrich	P1379	Original unspecified
Nonfat-Dried Milk	Reagent	Sigma-Aldrich	M7409	Original unspecified
Super Signal West Pico Substrate	Reagent	Thermo-Fisher (Pierce)	34087