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. 2014 Dec 10;3:e04037. doi: 10.7554/eLife.04037
KHM-3S IC50
Erlotinib 0.5 μM
Erlotinib + HGF >10 μM
Erlotinib + HGF + Crizotinib 0.3 μM

• HGF induces resistance to Erlotinib.

• Crizotinib blocks HGF-induced resistance to Erlotinib, restoring sensitivity.