KHM-3S | IC50 |
---|---|
Erlotinib | 0.5 μM |
Erlotinib + HGF | >10 μM |
Erlotinib + HGF + Crizotinib | 0.3 μM |
• HGF induces resistance to Erlotinib.
• Crizotinib blocks HGF-induced resistance to Erlotinib, restoring sensitivity.
KHM-3S | IC50 |
---|---|
Erlotinib | 0.5 μM |
Erlotinib + HGF | >10 μM |
Erlotinib + HGF + Crizotinib | 0.3 μM |
• HGF induces resistance to Erlotinib.
• Crizotinib blocks HGF-induced resistance to Erlotinib, restoring sensitivity.