TABLE 2 .
95% CIs |
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Brain Region | Nstudies | NTBI | Ncontrol | Mean dw | dw SE | Lower Limit | Upper Limit | Nfs | %OL | Q | Study References |
Composite whole brain | 2 | 22 | 20 | 1.61# | 0.36 | 0.89 | 2.33 | 11 | 12 | 3.75NS | Chu et al., 2010; Virji-Babul et al., 2013 |
Total Corpus Callosum | 1 | 10 | 10 | 1.42# | 0.03 | 2.80 | 6 | 31 | Wilde et al., 2008 | ||
Left Anterior Corona Radiata | 2 | 28 | 26 | 1.15# | 0.29 | 0.57 | 1.73 | 9 | 39 | 0.44NS | Borich et al., 2013; Mayer et al., 2012 |
Cerebral Peduncle | 1 | 16 | 16 | 1.13# | 0.08 | 2.19 | 4 | 40 | Mayer et al., 2012 | ||
Fornix | 2 | 23 | 21 | 1.12# | 0.32 | 0.48 | 1.76 | 9 | 39 | 0.54NS | Borich et al., 2013; Yallampalli et al., 2010 |
Right Anterior Corona Radiata | 2 | 28 | 26 | 1.04# | 0.29 | 0.47 | 1.61 | 8 | 43 | 0.12NS | Borich et al., 2013; Mayer et al., 2012 |
Superior Corona Radiata | 1 | 16 | 16 | 1.01# | −0.03 | 2.05 | 4 | 44 | Mayer et al., 2012 | ||
Left Cingulum Bundle | 1 | 12 | 11 | 1.00# | 0.13 | 1.87 | 4 | 44 | Wu et al., 2010b | ||
Right Anterior thalamic radiation | 1 | 12 | 10 | .91# | 0.02 | 1.78 | 3 | 48 | Borich et al., 2013 | ||
Right forceps minor | 1 | 12 | 10 | .90# | 0.02 | 1.78 | 3 | 48 | Borich et al., 2013 | ||
Left anterior thalamic radiation | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Right Inferior longitudinal fasciculus | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Right Inferior fronto-occipital fasciculus | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Left Inferior fronto-occipital fasciculus | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Subcallosal cortex | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Right thalamus | 1 | 12 | 10 | .89# | 0.01 | 1.77 | 3 | 48 | Borich et al., 2013 | ||
Left White Matter | 1 | 16 | 16 | .85# | 0.18 | 1.87 | 3 | 50 | Mayer et al., 2012 | ||
Right Cingulum Bundle | 1 | 12 | 11 | .79 | −0.06 | 1.64 | 3 | 53 | Wu et al., 2010b |
Note. #indicates moderate or large and significant effect, with adequate Nfs; Nstudies = Total number of studies included in analysis, NTBI = total number of participants in traumatic brain injury (TBI) group, Ncontrol = total number of Control participants, mean dw = mean weighted effect size, SE = standard error, 95% CIs = 95% confidence intervals, Nfs = Fail safe N,%OL = percentage overlap between the distribution of scores for the TBI and Control groups, NS = nonsignificant. A significant Q indicates a heterogeneous distribution. Where Q statistics were sig, as indicated by *, a random-effects model was used to calculate d. FA = fractional anisotropy.