Table IV.
Comparison of the gradation values of the obtained bands (Fig. 2A and B) as a result of different angiotensin II concentrations towards the expressions of MMP-9 mRNA and TIMP-1 mRNA in rat aortic vascular smooth muscle cells.
| Groups | Control | 10−9 M | 10−8 M | 10−7 M | 10−6 M |
|---|---|---|---|---|---|
| MMP-9 gradation | 1 | 1.28±0.11a | 1.36±0.11a | 1.58±0.10a | 1.92±0.13a |
| TIMP-1 gradation | 1 | 1.01±0.08 | 1.04±0.11 | 0.98±0.10 | 0.94±0.18 |
| MMP-9/TIMP-1 | 1 | 1.27±0.04a | 1.31±0.05a | 1.61±0.06a | 2.04±0.04a |
a
P<0.01 as compared with the control group. Values are presented as the mean ± standard deviation (n=4).
MMP-9, matrix metalloproteinase-9; TIMP-1, tissue inhibitor of metalloproteinase-1.