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. 2014 Nov 6;11(3):1777–1783. doi: 10.3892/mmr.2014.2892

Figure 4.

Figure 4

(A–D) hBMMSCs demonstrated pluripotent differentiation potential in vitro and in vivo. (A) In vivo osteogenesis test: Bone tissue formed subcutaneously on the back of the nude mice 35 days after hBMMSCs inoculation. (B) Histology results showed endochondral bone formation (hematoxylin and eosin staining, ×200) (C) Histology results showed simultaneous bone tissue formation (hematoxylin and eosin staining, ×100) (D) In vitro adipogenesis test: Sudan black B staining lipid droplets appeared at day 18 post 113 induction of adipogenesis. hBMMSCs, human bone marrow mesenchymal stem cells.