Table 3.
Comparisons of the optic disc parameters between moderate NTG and POAG patients (based on clinical assessment)
| Optic disc parameters | Mean ± SD
|
MD (95% CI) | T stat (df) | P-value* | |
|---|---|---|---|---|---|
| Moderate NTG (n=18) | Moderate POAG (n=20) | ||||
| Disc area, mm2 | 2.71±0.40 | 2.49±0.38 | 0.22 (−0.40–0.48) | 1.72 (36) | 0.095 |
| Cup area, mm2 | 1.38±0.33 | 1.17±0.37 | 0.21 (−0.02–0.44) | 1.82 (36) | 0.076 |
| Rim area, mm2 | 1.33±0.31 | 1.32±0.44 | 0.01 (−0.25–0.26) | 0.07 (36) | 0.945 |
| Cup volume, mm3 | 0.43±0.18 | 0.31±0.20 | 0.12 (0.00–0.25) | 1.98 (36) | 0.055 |
| Rim volume, mm3 | 0.30±0.11 | 0.28±0.18 | 0.02 (−0.08–0.12) | 0.40 (36) | 0.694 |
| Cup/disc area ratio | 0.51±0.10 | 0.47±0.14 | 0.04 (−0.04–0.12) | 0.94 (36) | 0.354 |
| Linear cup/disc ratio | 0.71±0.07 | 0.68±0.11 | 0.03 (−0.03–0.09) | 1.08 (36) | 0.288 |
| Mean cup depth, mm | 0.37±0.07 | 0.30±0.10 | 0.07 (0.01–0.13) | 2.44 (36) | 0.020 |
| Maximum cup depth, mm | 0.78±0.24† | 0.61±0.25† | – | 2.28‡ | 0.023¶ |
| Cup shape measure | −0.05±0.05 | −0.08±0.05 | 0.03 (−0.01–0.06) | 1.61 (36) | 0.117 |
| Height variation contour, mm | 0.38±0.09 | 0.36±0.09 | 0.02 (−0.04–0.08) | 0.67 (36) | 0.492 |
| Mean RNFL thickness, mm | 0.21±0.06 | 0.19±0.07 | 0.03 (−0.02–0.07) | 1.29 (36) | 0.207 |
| RNFL cross-sectional area, mm2 | 1.24±0.35 | 1.04±0.43 | 0.20 (−0.06–0.46) | 1.53 (36) | 0.135 |
Notes:
*
Independent t-test was applied.
†
Median (interquartile range).
‡
Z stat.
¶
Mann–Whitney test was applied. Bold text indicates that the values reached significant level.
Abbreviations: NTG, normal-tension glaucoma; POAG, primary open-angle glaucoma; SD, standard deviation; MD, mean difference; CI, confidence interval; df, degree of freedom; RNFL, retina nerve fiber layer.