Table 4.
Comparisons of the optic disc parameters between advanced NTG and POAG (based on clinical assessment)
| Optic disc parameters | Mean ± SD
|
MD (95% CI) | T stat (df) | P-value* | |
|---|---|---|---|---|---|
| Advanced NTG (n=14) | Advanced POAG (n=25) | ||||
| Disc area, mm2 | 2.58±0.42 | 2.31±0.37 | 0.26 (0.00–0.53) | 2.02 (37) | 0.050 |
| Cup area, mm2 | 1.74±0.46 | 1.44±0.38 | 0.29 (0.02–0.57) | 2.14 (37) | 0.039 |
| Rim area, mm2 | 0.84±0.36 | 0.87±0.33 | −0.03 (−0.26–0.20) | −0.26 (37) | 0.795 |
| Cup volume, mm3 | 0.62±0.35 | 0.53±0.24 | 0.09 (−0.11–0.28) | 0.92 (37) | 0.365 |
| Rim volume, mm3 | 0.11±0.09† | 0.13±0.13† | – | −0.95‡ | 0.340 |
| Cup/disc area ratio | 0.67±0.13 | 0.62±0.13 | 0.05 (−0.04–0.14) | 1.13 (37) | 0.264 |
| Linear cup/disc ratio | 0.82±0.08 | 0.78±0.08 | 0.03 (−0.03–0.09) | 1.10 (37) | 0.277 |
| Mean cup depth, mm | 0.36±0.11 | 0.39±0.13 | −0.02 (−0.11–0.06) | −0.54 (37) | 0.593 |
| Maximum cup depth, mm | 0.76±0.20 | 0.82±0.23 | −0.06 (−0.21–0.09) | −0.86 (37) | 0.393 |
| Cup shape measure | −0.02±0.07† | −0.06±0.06† | – | −1.39‡ | 0.163¶ |
| Height variation contour, mm | 0.39±0.24† | 0.30±0.14† | – | −1.20‡ | 0.229¶ |
| Mean RNFL thickness, mm | 0.10±0.13† | 0.13±0.10† | – | −1.64‡ | 0.101¶ |
| RNFL cross-sectional area, mm2 | 0.54±0.76† | 0.70±0.49† | – | −1.38‡ | 0.169¶ |
Notes:
*
Independent t-test was applied.
†
Median (interquartile range).
‡
Z stat.
¶
Mann–Whitney test was applied. Bold text indicates that the values reached significant level.
Abbreviations: NTG, normal-tension glaucoma; POAG, primary open-angle glaucoma; SD, standard deviation; MD, mean difference; CI, confidence interval; df, degree of freedom; RNFL, retina nerve fiber layer.