Table 6.
Comparisons of the optic disc parameters between advanced-stage NTG and POAG (based on AGIS score)
| Optic disc parameters | Median (interquantile range)
|
Z stat | P-value* | |
|---|---|---|---|---|
| Severe NTG (n=11) | Severe POAG (n=22) | |||
| Disc area, mm2 | 2.47 (0.60) | 2.28 (0.41) | −2.22 | 0.026 |
| Cup area, mm2 | 1.66 (0.61) | 1.40 (0.57) | −1.58 | 0.114 |
| Rim area, mm2 | 0.81 (0.34) | 0.85 (0.50) | −1.43 | 0.152 |
| Cup volume, mm3 | 0.63 (0.44) | 0.55 (0.45) | −1.80 | 0.071 |
| Rim volume, mm3 | 0.12 (0.09) | 0.13 (0.13) | −1.14 | 0.256 |
| Cup/disc area ratio | 0.67 (0.15) | 0.63 (0.20) | −0.07 | 0.941 |
| Linear cup/disc ratio | 0.82 (0.09) | 0.80 (0.13) | −0.07 | 0.941 |
| Mean cup depth, mm | 0.36 (0.13) | 0.39 (0.24) | −1.78 | 0.075 |
| Maximum cup depth, mm | 0.77 (0.24) | 0.83 (0.40) | −1.31 | 0.191 |
| Cup shape measure | −0.02 (0.07) | −0.05 (0.10) | −1.34 | 0.180 |
| Height variation contour, mm | 0.38 (0.24) | 0.32 (0.15) | −0.89 | 0.373 |
| Mean RNFL thickness, mm | 0.09 (0.14) | 0.13 (0.10) | −1.29 | 0.198 |
| RNFL cross-sectional area, mm2 | 0.52 (0.77) | 0.70 (0.53) | −1.68 | 0.093 |
Notes:
*
Mann–Whitney test was applied. Bold text indicates that the values reached significant level.
Abbreviations: NTG, normal-tension glaucoma; POAG, primary open-angle glaucoma; RNFL, retina nerve fiber layer; AGIS, Advanced Glaucoma Intervention Study.