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. Author manuscript; available in PMC: 2014 Dec 18.
Published in final edited form as: Cochrane Database Syst Rev. 2014 Nov 5;11:CD009561. doi: 10.1002/14651858.CD009561.pub2

Table 4.

Other types of keratoprosthesis for repeat corneal transplantation: non-randomized study characteristics and outcomes

Study Study design Study dates Country Follow-up Number of participants Number with repeat PK Funding source and declarations of interest

Ghaffariyeh 2011 Retrospective case series of the Fyodorov-Zuev KPro 2003-2007 Iran (Dr. Khodadoust Eye Hospital) Mean 52 months (range 28 to 84 months) 10 (10 eyes) 10/10 (100%) “None of the authors have any financial or proprietary interest in any material or method mentioned.”

Hille 2006 Retrospective case series the OOKP 1993-2004 Germany (University of Saarland) Median 2.9 years 25 (25 eyes) 18/25 (72%) NR
Study Number with BCVA ≥ 20/100 Other visual acuity outcomes Number of graft failures Number of device extrusions


1 year 2 years 5 years 1 year 2 years 5 years

Ghaffariyeh 2011 8/10 8/10 2/4 “Patients retained BUVA of 20/200-20/50 in 50%, 20/60-20/100 in 30%, 20/200 in 10% and 20/400 in 10% of cases. Overall, 90% had 1 year postoperative vision of 20/200 or better. Eyes had 20/200 or better in 70% of cases at the last follow-up (average 52 months).” 1/10 (10%) 2/10 (20%) 3/10 (30%) at 3 years; failure rate 30% during follow-up 3/10 (30%) during follow-up

Hille 2006 11/20 (55%) 7/14 (50%) 2/5 (40%) 79% achieved ambulatory vision of 20/400 at last follow up NR NR NR None reported

BCVA: best-corrected visual acuity

BUVA: best-uncorrected visual acuity

OOKP: osteo-odonto-keratoprosthesis

NR: not reported

PK: penetrating keratoplasty