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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Int J Cancer. 2014 May 30;136(1):98–107. doi: 10.1002/ijc.28963

Table 4.

Concordance of HPV and p16INK4a results in invasive anal cancer cases

p16INK4a Total
HPV DNA Negative Positive
Negative 45 (78.9%) 12 (21.1%) 57*
Positive 3** (5.1%) 56 (94.9%) 59
Total 48 68 116

Overall concordance: 87.1% (95%CI: 79.0–3.0%); Kappa index=0.741, p<0.0001 (95%CI: 0.620 to 0.862); The concordant cells are highlighted;

(*)

In only one HPV DNA negative anal cancer case from the 58 of the series the p16 was not performed due to lack of material;

(**)

These cases had a single HPV infection: HPV11, HPV16 or HPV18;

%: Row % (p16 results among each HPV results category).