. Author manuscript; available in PMC: 2014 Dec 18.

Published in final edited form as: Cochrane Database Syst Rev. 2011 Dec 7;(12):CD004916. doi: 10.1002/14651858.CD004916.pub3

Table 5.

Unit of analysis for included studies

Unit of analysis	Studies reporting each type of unit of analysis
The average of both eyes	10 studies: Adler 2006; Aller 2006; Chung 2002; Fulk 1996; Fulk 2002; PIR-205 Study; Sankaridurg 2010; Schwartz 1981; Shih 1999; Tan 2005
Right eye only	7 studies: Cheng 2010; CLAMP Study; Edwards 2002; Houston Study; Katz 2003; MIT study; Yen 1989
The average of both eyes or one eye only^*	2 studies: COMET Study; Hasebe 2008
Right and left eyes reported separately	2 studies: Jensen 1991; Pärssinen 1989
Eye randomized and treated	1 study: ATOM study
Not reported	1 study: Yang 2009

The average values of both eyes were used if the correlation coefficient was > 0.85 between eyes and the mean difference (MD) was not statistically significant; otherwise the eye with more myopic change was used for each child (COMET Study). The mean of both eyes or right eye only (Hasebe 2008).