Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Change in refractive error from baseline (1 year)	7	1266	Mean Difference (Random, 95% CI)	0.16 [0.07, 0.25]
1.1 Bifocal lenses	4	421	Mean Difference (Random, 95% CI)	0.16 [0.01, 0.32]
1.2 Progressive addition lenses	3	845	Mean Difference (Random, 95% CI)	0.17 [0.10, 0.24]
2 Change in refractive error from baseline (2 years)	7		Mean Difference (IV, Random, 95% CI)	Totals not selected
2.1 Bifocal lenses	4		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
2.2 Progressive addition lenses	3		Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
3 Change in refractive error from baseline (3 years)	2		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
3.1 Bifocal lenses	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
3.2 Progressive addition lenses	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
4 Change in axial length from baseline (1 year)	3	812	Mean Difference (Random, 95% CI)	−0.07 [−0.09, −0.04]
5 Change in axial length from baseline (2 years)	2	723	Mean Difference (IV, Fixed, 95% CI)	−0.05 [−0.10, −0.01]
6 Change in axial length from baseline (3 years)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
7 Change in corneal radius of curvature from baseline-Horizontal (3 years)	1		Mean Difference (IV, Fixed, 95% CI)	Totals not selected
7.1 At three years, horizontal	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]
7.2 At three years, vertical	1		Mean Difference (IV, Fixed, 95% CI)	0.0 [0.0, 0.0]