. 2014 Nov 18;53(49):7854–7865. doi: 10.1021/bi501396v

Table 2. EC₅₀ Values (nanomolar) of the Novel Analogues 16 and 17 against Selected Cancer Cell Lines in Comparison with Those of 1 and 2 and Selected Congeners 13, 15, and 18^a.

cancer cell line	2	18	15	13	16	17	1
MDA-MB-231	464	1.24 × 10³	47.6	172	157	87.4	11.9
HeLa	110	346	11.1	35.1	30.7	13.4	2.50
Jurkat	688	1.30 × 10³	51.8	175	112	115	18.0

See Figure 1 for structures.

Table 2. EC50 Values (nanomolar) of the Novel Analogues 16 and 17 against Selected Cancer Cell Lines in Comparison with Those of 1 and 2 and Selected Congeners 13, 15, and 18a.