Table 1. Distribution of Mn Levels in Biological and Environmental Mediaa.
biomarker (units) | time period | N | min | 25th | 50th | 75th | max | GM (GSD) |
---|---|---|---|---|---|---|---|---|
dentin (Mn:Ca AUC × 10 000) | second trimester | 57 | 0.18 | 0.46 | 0.59 | 0.74 | 1.86 | 0.60 (1.5) |
third trimester | 60 | 0.01 | 0.24 | 0.32 | 0.46 | 1.21 | 0.33 (2.0) | |
prenatal | 62 | 0.15 | 0.35 | 0.48 | 0.57 | 1.34 | 0.51 (1.5) | |
postnatal | 61 | 0.03 | 0.10 | 0.14 | 0.22 | 1.15 | 0.16 (2.0) | |
enamel (Mn:Ca AUC × 10 000) | second trimester | 58 | 0.10 | 0.18 | 0.27 | 0.42 | 1.35 | 0.30 (1.9) |
third trimester | 60 | 0.09 | 0.19 | 0.30 | 0.47 | 1.37 | 0.31 (2.0) | |
prenatal | 61 | 0.10 | 0.18 | 0.28 | 0.51 | 1.31 | 0.30 (1.8) | |
postnatal | 37 | <LOD | 0.11 | 0.16 | 0.19 | 1.09 | 0.16 (1.8) | |
blood (μg/L) | 26 weeks gestation | 53 | 4.34 | 12.5 | 14.8 | 18.5 | 32.8 | 14.6 (1.5) |
delivery | 53 | 6.66 | 16.5 | 20.3 | 27.9 | 35.7 | 20.7 (1.4) | |
cord | 59 | 20.74 | 31.4 | 40.5 | 50.6 | 72.4 | 39.9 (1.4) | |
child 24 months | 37 | 11.04 | 17.5 | 25.2 | 32.8 | 50.1 | 25.0 (1.5) | |
urine (μg/L) | 26 weeks gestation | 59 | 0.07 | 0.2 | 0.4 | 0.6 | 7.3 | 0.5 (2.4) |
child 24 months | 39 | <LOD | 0.3 | 0.6 | 1.1 | 16.1 | 0.8 (3.6) | |
house dust concentration (μg/g) | 18 weeks gestation | 46 | 37 | 135 | 170 | 200 | 414 | 153 (1.7) |
house dust loading (μg/m2) | 18 weeks gestation | 46 | 6.2 | 193 | 619 | 1,720 | 18,400 | 511 (5.9) |
GM = geometric mean; GSD = geometric standard deviation; LOD = limit of detection.