Table 1.
Correlation between PBK/TOPK expression and clinicopathological features in cervical cancer (X̅ ± s)
| Clinicopathological features | N | PU value | P value |
|---|---|---|---|
| Age (Years) | |||
| < 44 | 42 | 20.98±8.21 | 0.246 |
| ≥ 44 | 38 | 21.26±6.88 | |
| Histological type | |||
| Squamous cell carcinoma | 70 | 21.78±6.79 | 0.012 |
| Adenocarcinoma | 6 | 19.23±11.27 | |
| Adenosquamous carcinoma | 2 | 5.41±0.45 | |
| Carcinoid tumor | 1 | 27.96±0.00 | |
| Small cell carcinoma | 1 | 10.51±0.00 | |
| Differentiation | |||
| Poorly differentiated | 21 | 25.61±4.89 | < 0.0001 |
| Well to moderately differentiated | 55 | 19.82±7.67 | |
| Lymph node metastasis | |||
| Positive | 11 | 28.05±5.31 | 0.001 |
| Negative | 69 | 20.01±7.30 | |
| Vagina and cervix invasion | |||
| Positive | 6 | 24.06±1.65 | 0.008 |
| Negative | 74 | 20.88±7.81 | |
| TNM stage | |||
| I | 65 | 19.82±7.48 | < 0.0001 |
| II-III | 15 | 26.74±5.04 | |
| Tumor size (cm) | |||
| ≤ 1 | 26 | 18.37±8.37 | 0.037 |
| > 1 | 54 | 22.44±6.84 |