Table 3.
Correlation of AhR expression with clinical characteristics of breast cancers. The semi-quantitative analysis revealed that for each target protein examined, there was no significant Difference in staining intensity between grades, TNM, ER, PR, C-erbB2, Ki-67, AR, EGFR, Molecular subtype, except for P53 and histological types
| Variables | AhR expression | P value | |||
|---|---|---|---|---|---|
|
|
|||||
| Total n=220 | High n = 94 | Low n = 126 | |||
| Age | ≤50 | 127 | 56 | 71 | |
| >50 | 93 | 38 | 55 | 0.6319 | |
| Histology | Cancer in situ | 17 | 7 | 10 | |
| Invasive ductal cancer | 178 | 83 | 95 | ||
| Invasive lobular cancer | 13 | 3 | 10 | ||
| Other | 12 | 1 | 11 | 0.0296 | |
| Grade | I | 15 | 7 | 8 | |
| II | 176 | 70 | 106 | ||
| III | 22 | 13 | 9 | 0.2102 | |
| TNM | 0 | 17 | 7 | 10 | |
| I | 21 | 6 | 15 | ||
| II | 145 | 65 | 80 | ||
| III | 37 | 16 | 21 | 0.5720 | |
| ER status | Positive | 119 | 52 | 67 | |
| Negative | 101 | 42 | 59 | 0.7522 | |
| PR | Positive | 94 | 39 | 55 | |
| Negative | 126 | 55 | 71 | 0.7485 | |
| HER2 status | Positive | 149 | 59 | 90 | |
| Negative | 71 | 35 | 71 | 0.2832 | |
| Ki-67 status | Positive | 102 | 42 | 60 | |
| Negative | 118 | 52 | 66 | 0.6655 | |
| AR | Positive | 118 | 48 | 70 | |
| Negative | 102 | 46 | 56 | 0.5087 | |
| P53 | Positive | 151 | 57 | 94 | |
| Negative | 69 | 37 | 32 | 0.0272 | |
| EGFR | Positive | 36 | 16 | 20 | |
| Negative | 184 | 79 | 105 | 0.8672 | |
| Molecular subtype | Luminal A | 40 | 52 | 67 | |
| Luminal B | 94 | 42 | 59 | ||
| Her2-like | 52 | 39 | 55 | ||
| Basal-like | 34 | 55 | 71 | 0.9772 | |