Figure 4.

miR-29 mediates the process that wnt3a and phosphorylation of β-catenin induced by TGFβ1 in OFs. Effect of miR-29a/b/c precursors on the protein expression of β-catenin, p-β-catenin, wnt3a and β-actin in OFs in the presence (+) or absence (-) of TGFβ1 is shown. Expression of β-catenin and β-actin in all the groups is about the same. Expression of p-β-catenin and wnt3a is up-regulated by TGFβ1 and down-regulated by miR-29. Results are representative of those in three repeated experiments.