Table 3.
Univariate and multivariate analysis of clinicopathologicparameters with OS by Cox proportional hazards regression
| Variable | RFS hazard ratio (95% Cl) | P value |
|---|---|---|
| Age (< 60, ≥ 60) | 1.015 (0.791-1.302) | 0.907 |
| Gender (male, female) | 1.017 (0.795-1.300) | 0.894 |
| Tumor sizes (< 5, ≥ 5) | 1.162 (0.907-1.488) | 0.235 |
| Tumor site (colon, rectal) | 0.985 (0.775-1.252) | 0.903 |
| Histologic grade (Grade 1, Grade 2, Grade 3) | 0.990 (0.685-1.432) | 0.958 |
| Histology (Tubular, Mucinous) | 0.730 (0.500-1.604) | 0.102 |
| Depth of invasion (Mucosa and submucosa, myometrium, epicardial) | 1.403 (0.826-2.383) | 0.210 |
| Lymph node metastasis (yes, no) | 1.309 (1.018-1.684) | 0.036※ |
| MDR-1 | 2.048 (1.523-2.753) | 0.000※ |
| LRP | 1.273 (0.952-1.705) | 0.105 |
| TopII | 1.272 (0.933-1.732) | 0.128 |
| GST-π | 1.431 (1.048-1.955) | 0.024※ |
※
indicate statistical significant (p < 0.05).