α-NF exhibited a synergistic inhibition on NF-κB activation in RAW264 macrophages with PDTC, NF-κB inhibitor. A, B: α-NF and PDTC synergistically suppressed NF-κB activation. C: α-NF exerted a synergistic inhibition on IL-6 mRNA expression with PDTC, while did not rescue IL-10 suppression. D: α-NF had a synergistic suppression on TNF-α production with PDTC, but did not reverse IL-10 secretion. *: Compared with IDM, P < 0.05; #: Compared with IDM + PDTC, P < 0.05.