Table 1.
gene | SNP | Variation | MAFa | PCR primers | Putative microRNAs |
---|---|---|---|---|---|
TLR7 | Rs10127190 | [T/A] | NA | F 5’-ACGTTGGATGACTTGCCACTCTTTTACAGG-3’ | hsa-miR-19a, hsa-miR-19b |
R 5’-ACGTTGGATGCTTTCTTATCTCTCTGTGTC-3’ | |||||
TLR4 | Rs11536887 | [A/G] | 0.016 | F 5’-ACGTTGGATGCGAGTGACAAAGTGACAGAG-3’ | - |
R 5’-ACGTTGGATGAAGACGTGCTTCAAATATCC-3’ | |||||
MAP3K7 | Rs3734657 | [C/T] | 0.016 | F 5’-ACGTTGGATGAGAAGTCAGCAGCAGAAACG-3’ | hsa-miR-194, hsa-miR-212, hsa-miR-132 |
R 5’-ACGTTGGATGGTCTTTCTTTGCATATTTC-3’ | |||||
TOLLIP | Rs41314515 | [C/T] | 0.0028 | F 5’-ACGTTGGATGTGCACCCAAGAACAGGTGTG-3’ | hsa-miR-608 |
R 5’-ACGTTGGATGGATTCCCGTGAAAGAGCACC-3’ | |||||
TLR7 | Rs5743786 | [T/C] | 0.000 | F 5’-ACGTTGGATGAGGAGGACTCCAAGAGTGTG-3’ | hsa-miR-548a-3p, hsa-miR-548e, hsa-miR-548f |
R 5’ACGTTGGATGAGGAATCCATATAATTGGC-3’ | |||||
TLR7 | Rs72552316 | [C/T] | NA | F 5’-ACGTTGGATGGTAGGTGGACCATATGCATT-3’ | hsa-miR-1265, hsa-miR-4764-5p, hsa-miR-541-5p |
R 5’-ACGTTGGATGTTGGGCCTGCTTCTGGGTT-3’ | |||||
TLR6 | Rs5743823 | [T/C] | 0.005 | F 5’-ACGTTGGATGGGAAATTCAACTTAAGAAACC-3’ | hsa-miR-452 |
R 5’-ACGTTGGATGCCTCCAGACAGTTACTTACG-3’ | |||||
TLR4 | Rs7869402 | [C/T] | 0.092 | F 5’-ACGTTGGATGTTTAGGGAGACACAGATGGC-3’ | hsa-miR-539 |
R 5’-ACGTTGGATGACCTTCACACGTAGTTCTCC-3’ |
MAF (Minor Allele Frequency) was cited from http://www.ncbi.nlm.nih.gov/SNP.