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A photomicrograph of a section from the testis of a rat from group II showing ruptured seminiferous tubule (crossed arrow) with damaged and disorganized spermatogenic cells which are lifting off the basal lamina (asterisks) and some of them are exfoliated in the lumen of the tubule (curved arrows). Note the pyknotic nuclei (arrows), vacuoles (v) in the interstitial space, absence of spermatozoa (arrow heads) and multinucleated giant cells (tailed arrow) (H&E × 400).
