Table 2.
Staining intensity of tumor markers in PTC, controls and FED
| Group | n | CK19 | Galectin-3 | HBME-1 | |||||||
|
| |||||||||||
| 0 | 1+ | 2+~3+ | 0 | 1+ | 2+~3+ | 0 | 1+ | 2+~3+ | |||
|
| |||||||||||
| PTC | hptc | 26 | 0 | 2 | 24 | 2 | 14 | 10 | 5 | 10 | 11 |
| ptc | 17 | 0 | 2 | 15 | 0 | 10 | 7 | 1 | 2 | 14* | |
| C | 16 | 9 | 5 | 2 | 16 | 0 | 0 | 16 | 0 | 0 | |
| FED | 18 | 0 | 13 | 5Δ | 11 | 7 | 0☆ | 16 | 2 | 0☆ | |
|
| |||||||||||
| Group | n | CD56 | Claudin-1 | NGAL | |||||||
|
| |||||||||||
| 0 | 1+ | 2+~3+ | 0 | 1+ | 2+~3+ | 0 | 1+ | 2+~3+ | |||
|
| |||||||||||
| PTC | hptc | 26 | 19 | 5 | 2 | 2 | 6 | 18 | 1 | 5 | 20 |
| ptc | 17 | 15 | 2 | 0 | 2 | 1 | 14 | 2 | 2 | 13 | |
| Control | 16 | 0 | 0 | 16 | 16 | 0 | 0 | 16 | 0 | 0 | |
| FED | 18 | 1 | 4 | 13☆ | 5 | 13 | 0Δ | 5 | 8 | 5Δ | |
Abbreviation: No., the number of cases; PTC, all papillary thyroid carcinoma; hptc, papillary thyroid carcinoma coexisted with Hashimoto’s thyroiditis; ptc, papillary thyroid carcinoma without Hashimoto’s thyroiditis; Control, benign thyroid tissues; FED, follicular epithelial dysplasia showing PTC-like nuclear alterations in Hashimoto’s thyroiditis;
compared with hptc, P = 0.031;
compared with PTC and C, all P < 0.001;
compared with PTC, all P < 0.01.