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The expression of EMT markers, MMPs and ERK. A. CD147 overexpression decreased the level of E-cadherin and increased vimentin, enhanced the expression MMP-2 and MMP-9 in Caco-2 cells. B. CD147 knockdown upregulated E-cadherin and downregulated vimentin, suppressed the expression MMP-2 and MMP-9 in SW480 cells. C. CD147 overexpression induced the level of p-ERK in Caco-2 cells. D. CD147 knockdown reduced the level of p-ERKin SW480 cells.
