Table 2. Seroconversion rate (rabies virus neutralizing antibody (RVNA) titers ≥ 0.5 IU/ml) comparison between PVRV and PCECV with Zagreb or Essen regimen on different age groups at day 7 or day 365 post-immunization.
| Age groups | Day 7 | Day 365 | |||||
| PVRV | PCECV | Pb | PVRV | PCECV | Pb | ||
| Zagreb | <5 | 43.8% (7/16) | 42.9% (9/21) | 0.957 | 93.8% (15/16) | 90.5% (19/21) | 0.715 |
| 5∼18 | 73.7% (14/19) | 80.8% (21/26) | 0.572 | 94.7% (18/19) | 96.2% (25/26) | 0.821 | |
| 19∼60 | 75% (24/32) | 90.9% (30/33) | 0.053 | 93.8% (30/32) | 90.9% (30/33) | 0.666 | |
| >60 | 76.5% (13/17) | 77.4% (24/31) | 0.940 | 88.2% (15/17) | 78.8% (26/31) | 0.678 | |
| Total | 69.0% (58/84) | 75.7% (84/111) | 0.303 | 92.9% (78/84) | 90.1% (100/111) | 0.494 | |
| Pa | 0.114 | <0.001 | 0.872 | 0.486 | |||
| Essen | <5 | 16.7% (3/18) | 15.4% (4/26) | 0.909 | 100% (18/18) | 96.2% (25/26) | 0.400 |
| 5∼18 | 83.3% (15/18) | 72% (18/25) | 0.379 | 100% (18/18) | 96% (24/25) | 0.391 | |
| 19∼60 | 82.1% (23/28) | 78.8% (26/33) | 0.742 | 100% (28/28) | 97.0% (32/33) | 0.353 | |
| >60 | 35.3% (6/17) | 44.4% (12/27) | 0.548 | 88.2% (15/17) | 92.6% (25/27) | 0.624 | |
| Total | 58.0% (47/81) | 54.1% (60/111) | 0.584 | 97.5% (79/81) | 95.5% (106/111) | 0.457 | |
| Pa | <0.001 | <0.001 | 0.052 | 0.865 | |||
a
By χ2 test for comparison among four age groups.
b
By χ2 test for comparison between PVRV and PCECV.