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. 2014 Dec 18;9(12):e115239. doi: 10.1371/journal.pone.0115239

Table 1. Inclusion/exclusion criteria.

Inclusion Criteria Exclusion Criteria
Aged 18 years or older Any co-existent ocular disease, with the exception of mild cataracts
Either gender Inability to visualize the retina due to corneal or other ocular media opacities (corneal degenerations, dense cataracts, trauma, lid malposition)
A confirmed history of outer retinal degenerative disease such as retinitis pigmentosa or choroideremia Any ocular condition that predisposes the subject to rubbing their eyes
Remaining visual acuity of bare light perception or less in both eyes Cognitive deficiencies, including dementia or progressive neurological disease
Functional inner retina (ganglion cells and optic nerve), as shown by the ability to perceive light and/or a measurable corneal electrically evoked visual response Psychiatric disorders, including depression, as diagnosed by a qualified psychologist
A history of at least 10 years of useful form vision in the worse seeing eye Deafness or significant hearing loss, or the presence of a cochlear implant
Must be willing and able to comply with the testing and follow-up protocol demands (preferably residing within 1.5 hours of the investigational site) Poor general health or pregnancy, which would exclude them from obtaining a general anesthetic