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. 2014 Dec 18;9(12):e114972. doi: 10.1371/journal.pone.0114972

Table 1. Baseline characteristics of premenopausal and postmenopausal women.

Premenopause (n = 4229) Postmenopause (n = 3071) p-value
Age (years) 36.45±8.50 63.63±9.22 <0.001
Height (cm) 159.35±5.57 153.02±5.84 <0.001
Weight (kg) 57.40±9.19 56.68±8.58 0.001
BMI (kg/m2) 22.61±3.44 24.17±3.20 <0.001
Hb (g/dL) 12.83±1.18 13.11±0.97 <0.001
Serum Ferritin (ng/mL) 32.22±27.64 68.22±47.70 <0.001
Serum Vitamin D (ng/mL) 16.44±5.80 19.10±7.27 <0.001
Serum ALP (IU/L) 183.24±52.85 253.36±74.48 <0.001
Serum PTH (pg/mL) 66.67±23.49 68.13±29.87 0.446
Ca intake/day (mg) 467.06±300.56 419.17±392.40 <0.001
P intake/day (mg) 1042.90±435.36 945.38±430.67 <0.001
Total femur BMD (g/cm2) 0.90±0.11 0.77±0.12 <0.001
Femur neck BMD (g/cm2) 0.76±0.10 0.62±0.11 <0.001
Lumbar spine BMD (g/cm2) 0.99±0.12 0.80±0.14 <0.001
Resident district <0.001
Urban 2968 (70.2) 179 (58.4)
Rural 1261 (29.8) 1279 (41.6)
Education <0.001
Elementary 186 (4.4) 2039 (67.0)
Middle, High school 2301 (54.6) 880 (28.9)
University, College 1729 (41.0) 126 (4.1)
Occupation <0.001
Office type 3851 (91.5) 2178 (71.6)
Outfield type 360 (8.5) 866 (28.4)
Alcohol <0.001
Never 2163 (51.3) 2523 (82.4)
≤Once/month 1578 (37.4) 418 (13.7)
>Once/month, ≤Once/week, 395 (9.4) 85 (2.8)
>Once/week, ≤Everyday 84 (2.0) 35 (1.1)
Smoking <0.001
Never 3638 (88.5) 2790 (92.4)
Ever 193 (4.7) 95 (3.1)
Current 280 (6.8) 136 (4.5)
Physical activity 0.001
Low 2684 (63.7) 2071 (67.9)
Moderate 890 (21.1) 600 (19.7)
High 640 (15.2) 381 (12.5)
Dietary intake <0.001
Frequently difficult 14 (0.4) 57 (2.0)
Occasionally difficult 107 (2.8) 239 (8.5)
Enough, but not diverse 1932 (50.3) 1569 (55.5)
Diverse, Enough 1790 (46.6) 960 (34.0)
Personal history of fracture <0.001
Yes 101 (2.4) 637 (20.7)
Family history of fracture 0.797
Yes 723 (17.1) 518 (16.9)
HT <0.001
No 4138 (97.8) 2637 (85.9)
Yes 91 (2.2) 434 (14.1)

BMI: Body mass index, Hb: Hemoglobin, ALP: Alkaline phosphatase, PTH: Parathyroid hormone, Ca: Calcium, P: Phosphate, BMD: Bone mineral density, HT: Hormonal therapy.

Reference range: Hb 12.0–16.0 g/dL; Ferritin 10.0–130.0 ng/mL; Vitamin D 30.0–100.0 ng/mL; ALP 39.0–117.0 IU/L; PTH 10.0–57.0 pg/mL.