Table 6.

List of terms

Term	Definition
Autoregulation	The process by which the cerebral vasculature adjusts to maintain adequate blood flow
CBFV	Cerebral blood flow velocity
Circle of Willis	Circulatory structure that supplies blood to the brain
Constrained optimization	Solving a convex problem using by minimizing a cost function within given constraints
Craniospinal Compliance	The ability of the craniospinal system to accommodate additional volume
Fractional Factorial Experiment	Uses a carefully chosen subset of the parameter combinations from a full factorial experiment to reduce the necessary number of experimental runs
Full Factorial Experiment	An experimental design in which all combinations of parameters are tested. Requires 2^n experimental runs
Middle Cerebral Artery (MCA)	One of the major cerebral arteries originating from the CoW.
Parameter sensitivity	The degree to which a change in a parameter causes a change in the output
Pulse waveform shape	Shape of a pulsatile signal such as arterial blood pressure or cerebral blood velocity. The MOCAIP algorithm calculates 128 descriptive metric for wach pulse
Vascular active tension	The tension cerebral vasculature casued by the constriction or relaxation of smooth muscle cells in the vascular wall
Vascular elastic tension	The cerebral vasculature's natural resistance to stretching caused by the elastin and collagen fibers in the vascular wall
Vasodilation/Vasoconstriction	The increase/decrease in arteriole radius to maintain adequate cerebral blood flow. Effected by physical, chemical and neural stimuli