Table 1.
Demographics and baseline characteristics of the study patients
| Characteristic | No Strontium-89 (n=40) | Strontium-89 (n=39) | Total (n=79)* | |||
|---|---|---|---|---|---|---|
|
| ||||||
| n | % | n | % | n | % | |
|
| ||||||
| Extent of Disease (Stratification) | ||||||
|
| ||||||
| 1: ≤ 6 Bone Mets | 18 | 45.0% | 19 | 48.7% | 37 | 47% |
|
| ||||||
| 2: > 6 Bone Mets | 22 | 55.0% | 20 | 51.3% | 42 | 53% |
|
| ||||||
| Unknown | 0 | 0.0% | ||||
|
| ||||||
| Demographics | ||||||
|
| ||||||
| Age (years): | ||||||
|
| ||||||
| Range | 40 | 46–82 | 39 | 46–77 | 79 | 46–82 |
| Median | 63 | 62 | 63 | |||
|
| ||||||
| Race and Ethnicity: | ||||||
|
| ||||||
| White | 34 | 85.00% | 37 | 94.87% | 71 | 90% |
|
| ||||||
| Black | 3 | 7.50% | 2 | 5.13% | 5 | 6.25% |
|
| ||||||
| Not Reported | 3 | 7.50% | 0 | 0.00% | 3 | 3.75% |
|
| ||||||
| PSA (ng/mL): | 40 | 39 | 79 | |||
| Range | 0.1–124.6 | 0.1–995.6 | 0.1–995.6 | |||
| Median | 2.5 | 5.4 | 3.7 | |||
|
| ||||||
| LDH (IU/L): | 40 | 39 | 79 | |||
| Range | 152–1021 | 124–886 | 124–1021 | |||
| Median | 470 | 431 | 459 | |||
|
| ||||||
| Alkaline Phosphatase (IU/L): | 40 | 39 | 79 | |||
| Range | 31–2679 | 48–1212 | 31–2679 | |||
| Median | 127 | 99 | 127 | |||
|
| ||||||
| ECOG: | ||||||
|
| ||||||
| 0 | 22 | 55% | 29 | 74% | 51 | 65% |
|
| ||||||
| 1 | 16 | 40% | 9 | 23% | 25 | 31% |
|
| ||||||
| 2 | 0 | 0% | 0 | 0% | 0 | 0% |
|
| ||||||
| 3 | 2 | 5% | 1 | 3% | 3 | 4% |
|
| ||||||
| Gleason Score: | ||||||
|
| ||||||
| 10, 9, 8 | 24 | 60% | 26 | 67% | 50 | 63.3% |
|
| ||||||
| 7 | 11 | 27.5% | 9 | 23% | 20 | 25.3% |
|
| ||||||
| <7 | 0 | 0% | 1 | 2.3% | 1 | 1.3% |
|
| ||||||
| Not reported | 5 | 12.5% | 3 | 7.7% | 8 | 10.1% |
|
| ||||||
| Previous treatments: | ||||||
|
| ||||||
| Surgery only | 27 | 68% | 23 | 59% | 50 | 63% |
|
| ||||||
| Chemotherapy only | 1 | 3% | 1 | 1% | ||
|
| ||||||
| Combination therapy including surgery, chemotherapy and/or XRT | 7 | 17% | 7 | 18% | 14 | 18% |
|
| ||||||
| No prior therapy | 6 | 15% | 8 | 20% | 14 | 18% |
|
| ||||||
| Other features: | ||||||
|
| ||||||
| Lymph Node involvement | 6 | 15% | 8 | 20% | 14 | 18% |
|
| ||||||
| Visceral Metastasis | 0 | 0% | 0 | 0% | 0 | 0% |
One patient withdrew consent after the screening procedures. (Mets: Metastasis, PSA: Prostate specific antigen, LDH: Lactate dehydrogenase, XRT: Radiation theraphy)