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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Cancer. 2014 Jul 16;121(1):8–16. doi: 10.1002/cncr.28914

Figure 2. PI3K pathway is mutated and active in distinct TNBC subtypes.

Figure 2

(A) Heatmap displays the PI3K pathway mutations (red) across TNBC molecular subtypes extracted from the TCGA. (B) Boxplots show protein expression levels for phosphorylated AKT (top) and negative regulators PTEN and INPP4B in non-TNBC and TNBC subtypes. Mutation and RPPA data obtained from the cBioPortal (www.cbioportal.org) on 1–12–14.