FIG 5. Thyroid hormone signaling components are altered in offspring from obese dams at weaning.
mRNA expression of Dio1, Dio2, Dio3, Trα, Trβ, Ucp1, Ucp2 and Ucp3 in (A) liver, (B) mixed gastrocnemius muscle and (C) brown adipose tissue (BAT) of offspring from lean and obese rats at post-natal day 21 (N = 8 per group). Offspring from both lean and obese dams were cross-fostered to lean uncannulated surrogate dams on PND2, restricting exposure to maternal obesity to gestation alone. Average Ct values are provided for each gene as an indicator of relative abundance. Data are expressed as mean ± SEM. * indicates a statistically significant difference between Lean and Obese (P < 0.05).