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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Sep 23;7(6):830–837. doi: 10.1161/CIRCGENETICS.114.000556

Table 1. Association between uric acid transporter genetic risk score (instrumental variable) and serum urate, and between triglyceride genetic risk score and serum triglyceride.

Uric acid transporter Triglyceride
F-statistic R P F-statistic R P
ARIC Europeans All 114.81 0.0215 1.72E-26 76.82 0.0145 2.60E-18
Males 63.05 0.0256 3.08E-15 39.71 0.0163 3.53E-10
Females 99.25 0.0338 5.42E-23 36.56 0.0128 1.64E-09
FHS Europeans All 68.75 0.0226 1.69E-16 69.71 0.0228 1.32E-16
Males 29.68 0.0213 5.97E-08 36.28 0.0259 2.24E-09
Females 90.91 0.0536 5.58E-21 45.43 0.0275 2.20E-11
Combined All 187.37 0.0223 3.38E-42 137.29 0.0165 1.79E-31
Males 93.33 0.0242 7.97E-22 74.77 0.0195 7.51E-18
Females 183.43 0.0397 5.84E-41 65.5 0.0145 7.63E-16

The F-statistic represents the strength and R2 the percent variance in SU explained by the instrumental variable