Table 2.

Summary of major functional pathways associated with signature miRNAs

microRNA	Gene Set Description	# of Genes	Key Genes	P-value	FDR Q-Value
miR-150	Immune System	107	VAV1, RASGRP1/2	<0.001	<0.001
	Cytokine Signaling in Immune System	27	PTAFR	<0.001	<0.001
	Signaling by GPCR	53	CCXR3, CCL21	<0.001	<0.001
miR-30d	Melanogenesis	5	MITF, GNAI2, TYR	<0.001	0.005
	Developmental Biology	11	TGFB1, ITGA5	<0.001	<0.001
miR-15b	Cell Cycle	6	AURKB, CENPA	<0.001	<0.001
	Cell Cycle (mitotic)	6	AURKB, CENPA	<0.001	<0.001
	DNA Replication	5	AURKB, CENPA	<0.001	<0.001
miR-425	Up-regulated in ductal carcinoma tumor cells	2	CKS2, FAM54A	<0.001	0.005