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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Shock. 2015 Jan;43(1):24–30. doi: 10.1097/SHK.0000000000000251

Fig. 4. Effect of anti-CIRP antibody treatment on systemic and local proinflammatory cytokine IL-6 levels after hepatic I/R.

Fig. 4

Serum samples and ischemic liver tissues were collected at 24 h post-hepatic I/R from sham, vehicle and anti-CIRP antibody-treated (Anti-CIRP) groups. IL-6 protein levels in serum (A) and liver tissue (B) were determined by enzyme-linked immunosorbent assay. (C) Liver IL-6 mRNA expression was determined by qPCR analysis and its levels were normalized to β-actin. The value in sham group is designated as 1 for comparison. Data presented as means ± SE (n=6-7/group) and compared by one-way ANOVA and SNK method; *p < 0.05 vs. sham; #p < 0.05 vs. vehicle.