Table 3.

Hot flashes (HF) and body composition at baseline, follow up, and change from baseline to follow up (intent to treat)

			Weight Loss (N=21)		Control (N=19)		p
			median	IQR	median	IQR
Baseline	HF/24 hrs	Physiologic (#)	9.90	5.09, 13.19	6.98	2.99, 13.82	0.29
		Self report (#)	7.27	5.76, 9.99	5.65	3.35, 8.65	0.12
	HF/2 wk (#, Questionnaire)		70.00	35.00, 112.00	70.00	15.00, 112.00	0.50
	HF Severity		1.33	1.19, 1.71	1.42	1.29, 1.89	0.42
	HF Bother		1.33	1.17, 1.71	1.53	1.20, 1.89	0.39
	Weight (kg)		82.27	76.36, 87.05	85.91	78.64, 99.09	0.18
	% fat		44.90	41.20, 47.60	46.00	4.00, 13.00	0.53
Follow up	HF/24 hrs	Physiologic (#)	6.54	2.95, 12.91	8.09	2.00, 14.45	0.98
		Self report (#)	4.85	2.66, 6.34	4.14	2.01, 6.24	0.56
	HF/2 wk (#, Questionnaire)		22.00	6.00, 49.00	55.50	14.00, 70.00	0.13
	HF Severity		1.17	1.00, 1.38	1.42	1.27, 1.86	0.03
	HF Bother		1.17	1.00, 1.41	1.42	1.29, 1.86	0.045
	Weight (kg)		77.73	67.27, 84.55	85.45	77.05, 97.73	0.01
	% fat		41.30	35.05, 44.50	46.00	41.00, 48.00	0.03
Change	HF/24 hrs	Physiologic (#)	−1.73	−5.39, 0.01	0.00	−3.98, 0.97	0.31
		Physiologic (%)	−18.43	−53.62, 0.14	0.00	−57.44, 29.92	0.56
		Self report (#)	−1.93	−4.54, 0.00	−1.26	−2.78, 0.00	0.73
		Self report (%)	−28.74	−59.41, 0.00	−24.64	−51.48, 0.00	0.71
	HF/2 wk (#, Questionnaire)		−42.00	−70.00, 0.00	−14.50	−28.00, 12.00	0.09
	HF Severity		0.00	−0.37, 0.00	0.00	−0.31, 0.13	0.23
	HF Bother		0.00	−0.33, 0.00	0.00	−0.26, 0.13	0.35
	Weight (kg)		−7.50	−10.00, −3.18	0.00	−1.36, 1.59	<.0001
	Weight (%)		−8.95	−13.83, −3.45	0.00	−1.38, 1.42	<.0001
	% fat		−3.75	−6.65, −2.00	−0.50	−1.20, 0.60	<.0001

Note: Diary HF bothersome and severity scores ranged from 1–4 and were averaged over the monitoring period. Questionnaire HF frequency was recalled frequency of hot flashes over past two weeks (number HF/day*number of days experiencing HF)

Differences tested via Wilcoxon test