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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Circ Cardiovasc Genet. 2014 Nov 3;7(6):903–910. doi: 10.1161/CIRCGENETICS.114.000533

Figure 4.

Figure 4

Renal fibrosis was assessed on a 1–5 scale as described 2 in Picro-sirius red stained sections of kidney at the conclusion of the treatment period. Fibrosis was more severe in untreated SHR-A3 than in SHR-B2. Treatment with MMF was associated with a marked reduction in tubulo-interstitial injury in SHR-A3 (p<0.001), but had no effect in SHR-B2. Group sizes: SHR-A3 control n = 10, SHR-A3 MMF treated n = 10, SHR-B2 control n = 8, SHR-B2 MMF treated n = 11.