Figure 5.
Renal lymphocyte infiltration was assessed by immunohistochemistry using a rat anti-CD43 antibody. Lymphocyte infiltration was extensive in untreated 25 week old SHR-A3, and was minimal in untreated SHR-B2. Treatment of SHR-A3 rats with MMF was associated with significant reductions in lymphocyte infiltration to levels indistinguishable from that in untreated SHR-B2 rats (p<0.001). Group sizes: SHR-A3 control n = 10, SHR-A3 MMF treated n = 6, SHR-B2 control n = 8, SHR-B2 MMF treated n = 8.