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. 2014 Jun 18;19(2):260–270. doi: 10.1002/ejp.544

Figure 6.

Figure 6

Intrathecal injection of TNF antagonist etanercept reduces carrageenan-induced spinal JNK1/2 activation. Bar graphs depicting percent (%) change of (A) p-JNK1 and (B) p-JNK2 in the lumbar ipsilateral spinal cord 1 h after carrageenan injection in the presence of i.t. etanercept (100 μg), compared with vehicle (saline) injected control rats. Representative western blot images showing immunopositive bands from spinal cord homogenates for p-JNK1/2, total JNK1/2 (t-JNK1/2) and β-actin (loading control). All data are presented as mean ± SEM, **p < 0.01; ***p < 0.001, versus vehicle controls.