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Median PSA (IQR) associated with adverse changes in presenting disease characteristics, JHH PCa MDC 2008–2012
| PSA if no | PSA if yes | p | |
|---|---|---|---|
| Gleason up-graded | 5.7 (4.3, 9.4) | 6.9 (4.7, 21.0) | 0.005* |
| DRE up-staged | 5.6 (4.2, 10.0) | 6.0 (4.0, 15.1) | 0.294* |
| N0 to N1 | 6.4 (4.6, 12.6) | 12.9 (8.3, 42.9) | 0.001* |
| M0 to M1 | 6.4 (4.6, 12.1) | 31.0 (13.5, 77.9) | <0.001* |
| NCCN risk up-classified | 6.5 (4.6, 13.0) | 9.7 (5.4, 28.9) | *0.007 |
Wilcoxon-Mann-Whitney rank-sum test
