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. 2014 Jul 31;23(25):6807–6814. doi: 10.1093/hmg/ddu397

Figure 2.

Figure 2.

The UB in the Wnt5a mutant grows out as a doublet without anterior expansion of the Gdnf expression domain. (A) WISH for c-Ret using E10.5 embryos. left: Wnt5a fl/+;T-Cre; right: Wnt5a fl/Δ;T-Cre. (B) WISH for c-Ret using E11.5 embryos. left: Wnt5a fl/+;T-Cre; right: Wnt5a fl/Δ;T-Cre. (C) Calbindin staining of E11.5 explants of metanephric rudiments cultured for 24 h. left: Wnt5a fl/+;T-Cre; right: Wnt5a fl/Δ;T-Cre. (D) WISH for Gdnf using E10.5 embryos. left: Wnt5a fl/+;T-Cre; right: Wnt5a fl/Δ;T-Cre. White arrows label the UB (A) or UB stalk (B and C). A red-dotted ellipse marks Gdnf expression (D) with a yellow line for length and red line for width.