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. 2014 Jul 15;23(24):6528–6541. doi: 10.1093/hmg/ddu371

Figure 6.

Figure 6.

Effect on growth factors and neurogenesis. (A) BDNF mRNA was comparable. (B) VEGF mRNA was higher in the combined OAA group. (C) DCX mRNA was higher in the 1 g/kg/day, 2 g/kg/day and combined OAA groups. (D) Representative confocal microscopy pictures of the hippocampal dentate gyrus. The top image used the ×10 objective, the bottom image represents an enlarged view of the boxed area from the 10× picture. (E) Dentate gyrus DCX pixel density was higher in the 2 g/kg/day OAA group. (F) Mice in the 1 g/kg/day, 2 g/kg/day and combined OAA groups had more intensely DCX-positive neurons. (G) Mice in the 1 g/kg/day, 2 g/kg/day and combined OAA groups had longer DCX-positive neurites. Values shown are relative group means ± SEM. *P < 0.05; **P < 0.005.